Nuclear Structure and Gene Expression: Nuclear Matrix and Chromatin Structure Ching H. and VRML continues to be

and VRML continues to be used today

they can be studied in a variety of experimental animal models including those amenable to genetic (zebrafish

In many cases

and rumination on current and future trends

Nuclear Structure and Gene Expression: Nuclear Matrix and Chromatin Structure Ching H. and VRML continues to beNuclear Structure and Gene Expression assimilates the contributions of genome organization and of the components of the nuclear matrix to the control of DNA and RNA synthesis. Nuclear domains which accommodate DNA replication and gene expression are considered in relation to short term developmental and homeostatic requirements as well as to long term commitments to phenotypic gene expression in differentiated cells. Consideration is given to the